Over the last century, light has been a pivotal tool in visualizing and studying biological systems. The world of optics and imaging has exploded to touch nearly every research niche of bio-medicine imaginable, clinically and experimentally. With that, complexity in developing and applying such systems has grown exponentially – pulling from the knowledge of scientists, clinicians, and engineers. And while optical instrumentation is more adaptable and accessible than ever, the learning curve can be pretty steep. Adapting and developing custom optical instruments for research is the future of scientific imaging.
Utilizing sophisticated high-powered lasers for both targeted contrast and label-free imaging offers unique perspectives in modern biomedical imaging. The possibilities of imaging deep into live tissue structure and observe physiological function in real-time provides a powerful research tool. There are many novel and practical applications of nonlinear imaging waiting to be realized.
As our understanding of the brain grows, new tools are critical to acquiring and synthesizing this knowledge. Understanding the brain extends beyond just how networks of neurons connect and interact, but how other cells such as astrocytes, microglia, oligodendrocytes, and vasculature function in concert to allow the brain to work so effectively. There is a critical need for tools and techniques to study these cellular interactions is critical to understanding how the brain works at the cellular, whole organ, and behavioral levels.
Bringing cutting edge code and data infrastructure to load, synthesize, and analyze large multidimensional imaging data repeatably, accurately, and automated is crucial for scientists to begin applying cutting edge imaging tools to advance science. The most advanced imaging systems in the world are useless without the right infrastructure and software tools. Making these resources as widely accessible as possible will drive biomedical research forward in directions waiting to be explored.
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